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PublicationInternational Journal of Unconventional Computing
Year2010
Volume6
Pages451-460
International

Enzymatic Logic Gates with Noise-Reducing Sigmoid Response

Authors:Valber Pedrosa , Dmitriy Melnikov , Marcos Pita Martínez, Jan Halamek , Vladimir Privman , Aleksandr Simonian , Evgeny Katz
Groups of research:BioElectroCatalysis
Biochemical computing is an emerging field of unconventional computing
that attempts to process information with biomolecules and biological
objects using digital logic. In this work we survey filtering in general, in
biochemical computing, and summarize the experimental realization of
an AND logic gate with sigmoid response in one of the inputs. The logic
gate is realized with electrode-immobilized glucose-6-phosphate dehydrogenase
enzyme that catalyzes a reaction corresponding to the Boolean
AND functions. A kinetic model is also developed and used to evaluate
the extent to which the performance of the experimentally realized logic
gate is close to optimal.
Keywords:Biocomputing, enzyme logic, logic gate, binary logic, sigmoid response
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