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PublicationInternational Journal of Unconventional Computing
Year2012
Volume5-6
Pages391-417
International

Switchable Biofuel Cells Controlled by Biomolecular Computing Systems

Authors:Marcos Pita Martínez
Groups of research:BioElectroCatalysis
Almost every existing device includes either a control or a self-regulation
system. This is also the case of a new alternative energy source, the biofuel
cells. Fuel cells take advantage of natural existing compounds in biofluids
and transform them into energy available in situ. Although being a promising
approach to solve energy supply, particularly in small implantable
devices, these systems does not produce enough energy to support a conventional
computing system together with their natural functionality.
Enzyme biocomputing is an unconventional computing approach that
assembles enzyme-catalyzed chemical reactions into Boolean logic operations,
therefore can enhance the applications of biofuel cells. Enzyme
logic gates can control a switch responsible of the biofuel cell power output
in such a way that each specific combination of input signals–related
to physiological conditions– determine whether the biofuel cell must provide
energy or not and provoke an in situ real time response, i.e. drug
release. Herein I review the most significant advances from the most basic
enzyme logic gates to a final prototype of implantable biofuel cell controlling
an acetaminophen dispenser depending on biologic marker inputs.
Keywords:enzyme logic, Biofuel cell, implantable devices, switchable electrodes
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