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Dátos técnicos
Año2016
No. Solicitud-
Alcance
StatusAño de prioridad
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Improved enzyme for metabolites and drug synthesis

Autores:Miguel Alcalde Galeote
The Institute of Catalysis and Petrochemistry has generated a proteic variation of the peroxigenase from the Agrocybe aegerita fungi, with enhanced properties of catalytic activity, stability and heterologous expression capacity. The mutant enzyme has been designed to be applied in aromatic hydroxylation reactions, especially for 5’-hydroxipropranolol synthesis. Enzyme producers, or pharma companies, interested in the use of this enzyme for the production of human drug metabolites and other drugs, under patent license, are sought.
Palabras clave:enzimas, síntesis, metabilitos, fármacos
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